Yes, the side effects of metformin can be managed or prevented. Here are some tips for managing or preventing the side effects of metformin:
- Take metformin on a schedule: Taking metformin on a schedule can help reduce side effects. Most metformin side effects are short-term, which is 2 weeks or less.1
- Take metformin with food: Taking metformin with food can help reduce the chances of feeling sick. It may also help to slowly increase your dose over several weeks.2
- Stay hydrated: Take small, frequent sips of water or squash to avoid dehydration.2
- Avoid alcohol: Alcohol can increase the risk of lactic acidosis, a rare but serious side effect of metformin.3
- Avoid certain medications: Metformin interacts with a few medications. These medications can make metformin less effective or increase the risk of side effects. Notable medications that interfere with it include thiazide diuretics, corticosteroids, estrogen-containing medications, and carbonic anhydrase inhibitors.1
- Monitor vitamin B12 levels: Taking metformin can cause vitamin B12 deficiency if taken for a long time. This can make you feel very tired, breathless, and faint, so your doctor may check the vitamin B12 level in your blood. If your vitamin B12 levels become too low, vitamin B12 supplements will help.2
- Consult your doctor: If any side effects occur, the patient should consult their doctor immediately13.2
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