Endometriosis is a condition where tissue similar to the lining of the uterus, called the endometrium, grows outside of the uterus
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Endometriosis can occur in women from the onset of their first period (menarche) through menopause
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The primary symptom of endometriosis is pelvic pain, often associated with menstrual periods
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- Excessive menstrual cramps
- Abnormal or heavy menstrual flow
- Pain during intercourse
- Difficulty getting pregnant46
The pain in endometriosis often comes back periodically because the tissue outside the uterus still responds to hormonal changes that occur during the menstrual cycle
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The exact cause of endometriosis is unknown, but there are several theories. It is thought to arise due to a combination of genetic, hormonal, and immune system factors
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- Retrograde menstruation: Menstrual blood containing endometrial cells flows back through the fallopian tubes and into the pelvic cavity, where the cells can implant and grow.5
- Transformation of peritoneal cells: Cells in the lining of the pelvic cavity may transform into endometrial-like cells.5
- Embryonic cell transformation: Hormones or immune factors may transform embryonic cells into endometrial-like cells.5
- Surgical scar implantation: Endometrial cells may attach to surgical incisions made in the pelvic area.5
To diagnose endometriosis, a doctor may perform a pelvic exam, review your symptoms and medical history, and may order additional tests such as:
- Ultrasound: This imaging test uses sound waves to create images of the pelvic organs.6
- MRI: Magnetic resonance imaging can provide detailed images of the pelvic area.6
- Laparoscopy: This minimally invasive surgical procedure allows the doctor to view the pelvic organs and take tissue samples for biopsy.4
The treatment for endometriosis depends on the severity of symptoms, desire for future pregnancies, age, and the extent of the condition
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- Pain medication: Over-the-counter pain relievers or prescription medications can help manage pain.1
- Hormone therapy: Hormonal medications can help regulate the menstrual cycle and reduce the growth of endometrial tissue.1
- Surgery: In more severe cases, surgery may be necessary to remove endometrial implants, scar tissue, or cysts.3
Surgery may be needed for endometriosis in more severe cases, especially if the condition is causing significant pain or fertility issues
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Medications commonly used to treat endometriosis include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs): These can help relieve pain and reduce inflammation.1
- Hormonal contraceptives: Birth control pills, patches, or vaginal rings can help regulate the menstrual cycle and reduce endometrial tissue growth.1
- Gonadotropin-releasing hormone (GnRH) agonists: These medications suppress the production of estrogen, which can help shrink endometrial tissue.1
- Progestin therapy: Progestin-only medications can help regulate the menstrual cycle and reduce endometrial tissue growth.1
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