HDL does not protect against heart disease – A New Study


High-density lipoprotein (HDL), also known as useful cholesterol, may not be as helpful in predicting and protecting against heart disease risk as previously thought, according to a study funded by the National Institutes of Health.



Research conducted in the 1970s found that higher levels of HDL cholesterol were associated with a lower risk of heart disease. This relationship has since been widely accepted and used for cardiovascular risk assessments. Although that research was done only on white Americans.


Recently, a study published in the Journal of the American College of Cardiology found that low levels of HDL cholesterol in white Americans were associated with a stronger risk of heart attack, while this observation was not correct in black Americans.


At the same time, the research also found that high amounts of HDL cholesterol in both groups did not cause a reduction in the risk of heart disease.


"It was believed that low levels of HDL cholesterol are harmful, regardless of who belongs to which race," said study senior author Nathalie Palmer in a news release. These ideas were tested in this study. The results may mean that in the future we won’t get a slap from a doctor if HDL levels are high.



Researchers used data from thousands of people who were part of the Reasons for Geographic and Facial Differences in Stroke (REGARDS) group. Participants were 45 years old at the time of joining the program between 2003 and 2007, and their health was assessed for an average period of 10 years.



Researchers found that low-density lipoprotein (LDL), known as harmful cholesterol, and high amounts of triglycerides were a very modest predictor of heart disease in black and white people.



But more research is needed to understand what is causing racial differences in the risk of HDL and heart disease, the researchers said.


This e-mail and any attachments are confidential and intended solely for the addressee and may also be privileged or exempt from disclosure under applicable law. If you are not the addressee, or have received this e-mail in error, please notify the sender immediately, delete it from your system and do not copy, disclose or otherwise act upon any part of this e-mail or its attachments. Any opinion or other information in this e-mail or its attachments that does not relate to the business of HBL is personal to the sender and is not given or endorsed by HBL. Internet communications are not guaranteed to be secure or virus-free. HBL does not accept responsibility for any loss arising from unauthorised access to, or interference with, any Internet communications by any third party, or from the transmission of any viruses. Replies to this e-mail may be monitored by HBL for operational or business reasons.