Iodized Salt and Hashimoto’s Disease: Myths Debunked

Does Salt Iodization Cause Hashimoto’s Disease?

When we buy salt, we often reach for the one with the note “iodized”. This means that iodine has been added to the salt. It is a microelement necessary for the proper functioning of the body. Both deficiency and excess of this element have serious health consequences, especially the thyroid gland. Many people are concerned that eating salt with added iodine leads to Hashimoto’s disease. Is it true?

Significant iodine deficiency causes hypothyroidism, including its most common form – Hashimoto’s disease. Long-term exposure to large amounts of iodine can also lead to Hashimoto’s disease. Excess of this element primarily promotes enlargement of the thyroid gland. It causes hyperthyroidism of this gland and increases the risk of developing thyroid cancer. So it turns out that the most important thing in iodine intake is to maintain the “golden mean”.

We acquire iodine from the environment and through our diet. It is present in the air, water, plants, and animals that we consume. The problem is that its amount is not evenly distributed in the environment. Our areas are not very rich in this element. Therefore, in order to improve the health of Poles, in 1997 the obligation to iodize table salt was introduced. It is salt intended for use in households (the obligation does not apply to many types of salt, e.g. Himalayan salt, sea salt, so read the labels, and salt used in the food industry).

Recent research on iodine’s effects on Hashimoto’s thyroiditis highlights its dual role in thyroid health. While iodine is essential for thyroid hormone synthesis, excessive intake may exacerbate autoimmune thyroid conditions like Hashimoto’s. A 2021 study published in Nutrients (https://www.mdpi.com/2072-6643/13/2/515) found that high iodine levels can increase oxidative stress and thyroglobulin immunogenicity, potentially worsening autoimmune responses. Another 2020 review in Frontiers in Endocrinology (https://www.frontiersin.org/articles/10.3389/fendo.2020.00478/full) emphasized the importance of individualized iodine intake, as both deficiency and excess can disrupt thyroid function. Additionally, a 2022 study in Thyroid (https://www.liebertpub.com/doi/10.1089/thy.2021.0667) suggested that moderate iodine restriction might benefit some Hashimoto’s patients by reducing thyroid autoantibody levels. These findings underscore the need for careful iodine management in individuals with Hashimoto’s disease.

Does iodizing salt cause Hashimoto’s disease?

This is a popular myth. Iodizing table salt does not give so much element to the body to cause any harm. Although excess iodine can actually promote the development of Hashimoto’s disease or worsen its course, as research shows. This applies mainly to people who are genetically predisposed to develop the disease, especially with selenium deficiency. Polish experts agree that the benefits of a common salt iodization program outweigh the possible risks.

Is it worth supplementing iodine?

If hypothyroidism is not caused by iodine deficiency, there is no need for supplementation of this element. Do not take high doses of iodine, Lugol’s liquid or other preparations with iodine without consulting a doctor.

The daily requirement for iodine is:

  • children up to 5 years of age: 90 μg,
  • children 6-12 years: 120 μg,
  • children > 12 and adults: 150 μg,
  • pregnant and lactating women: 250 μg.

A simple way to check the level of this microelement in the body is to test urine for iodine concentration. In healthy people, kidneys excrete 90% of it. For adults, urinary excretion of iodine should be at least 100 micrograms per liter. It should not exceed 200-300 micrograms per liter.

Do we take the right amount of iodine with our diet?

Table salt is the main source of iodine in the diet. One teaspoon of iodized salt (5 g) contains about 150 micrograms of potassium iodide. Iodine constitutes about 77% of potassium iodide. This amount does not meet the daily requirement of an adult. The source of iodine is also a diet. Algae, sea fish, and seafood contain a lot of iodine. Plants that grew in soils with high iodine content also contain this element. The closer to the sea, the more iodine is found. The least amount of this element occurs in mountainous areas. Remember that you should not overdo it with salt. The WHO recommends limiting its consumption to 5 g per day…

Everything indicates that many people are at risk of iodine deficiency. The Krakow declaration on iodine was signed in 2018 by scientists from 27 countries. According to this declaration, iodine deficiencies occur almost throughout Europe. Children, pregnant women and pregnant women are particularly exposed to them. Scientists suggest in the document that governments should make it mandatory to add iodine to industrial salt. This salt is used as an additive to food products.

What salt should I use for Hashimoto’s disease?

Nutritionists currently recommend that you choose iodized salt regardless of whether you have Hashimoto’s disease or not. The Institute of Institute’s research shows that a diet without iodized salt lacks adequate iodine. This amount is too little compared to recommended standards. This increases the risk of deficiencies of this element.

The obligation to iodize salt has been introduced. Since then, the number of goiter of the thyroid gland has decreased significantly. The incidence of thyroid cancer has also decreased significantly. Of course, it is worth remembering not to exceed the recommended amount of salt. Its excess also promotes other diseases, such as hypertension. A reasonable approach seems to be to check the level of iodine in the body. It is also important to consult an endocrinologist who can professionally assess our need for additional iodine.

Symptoms of Autoimmune Disorders of the Thyroid

Autoimmune thyroid disorders, including Hashimoto’s disease and autoimmune thyroiditis, arise from the immune system’s attack on healthy thyroid tissue. Symptoms of these conditions may differ; however, some prevalent ones include:

– Fatigue and sluggishness

– Increased sensitivity to cold

– Increased sleepiness

– Dry skin

– Constipation

– Muscle weakness

– Muscle aches, tenderness, and stiffness

– Joint pain and stiffness

– Irregular or excessive menstrual bleeding

– Depression

– Problems with memory or concentration

– Swelling of the thyroid (goiter)

– A puffy face

– Brittle nails

– Hair loss

– Enlargement of the tongue

It is crucial to acknowledge that initial symptoms may not manifest in certain individuals, and the range of symptoms is broad and non-discriminatory towards the disorder [1][2][3][4]. In instances where thyroid disease has been diagnosed, medical practitioners may recommend a TPO antibody test and other thyroid tests as part of investigative measures to identify the underlying cause [5].

If you are encountering any of these indications, it is essential to seek medical attention for accurate diagnosis and management. The management approach for autoimmune disorders affecting the thyroid gland typically entails replacement therapy with thyroid hormones[1].

References

1. https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease

2. https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855

3. https://www.webmd.com/women/whatis-autoimmune-thyroiditis

4. https://www.hopkinsmedicine.org/health/conditions-and-diseases/hashimotos-thyroiditis

5. https://my.clevelandclinic.org/health/diseases/17665-hashimotos-disease

Citations:

[1] https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855

[2] https://www.webmd.com/women/whatis-autoimmune-thyroiditis

[3] https://www.hopkinsmedicine.org/health/conditions-and-diseases/hashimotos-thyroiditis

[4] https://my.clevelandclinic.org/health/diseases/17665-hashimotos-disease

[5] https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease

Hypothyroidism can cause dry skin, fatigue, and a cold feeling.

The thyroid gland is located in the front center of the neck, between the trachea and the larynx. It is the organ that produces the hormones triiodothyronine (T3), thyroxine (T4), and calcitonin. The thyroid requires iodine from food and the environment to produce them. The pituitary gland produces the hormone TSH, which regulates thyroid function.

Thyroid hormones affect many different processes and organs throughout the body, including:

  • metabolism,
  • energy use,
  • muscular strength,
  • fertility and potency,
  • heart work,
  • the functioning of the nervous system,
  • mental well-being,
  • condition of skin, hair and nails.

A deficiency of thyroid hormones therefore adversely affects many processes in the body. both adults and children, who can also get sick.

Causes of hypothyroidism

A variety of factors can contribute to hypothyroidism. They can be primary (caused by thyroid gland damage) or secondary (resulting from abnormalities in the functioning of the pituitary gland or hypothalamus).

The primary causes of hypothyroidism  are:

  • Hashimoto’s disease, otherwise chronic autoimmune thyroiditis,
  • postpartum thyroiditis,
  • radioiodine treatment,
  • neck radiotherapy,
  • significant iodine deficiency,
  • the use of certain medications (so-called drug-induced hypothyroidism), e.g. lithium salts, interferon, amiodarone,
  • surgical removal of the thyroid gland,
  • damage to the thyroid gland as a result of a disease, e.g. cancer,
  • congenital hypothyroidism.

Causes of secondary hypothyroidism  include:

  • hypothalamic or pituitary tumors,
  • injury or inflammation in the hypothalamus or pituitary gland,
  • Sheehan’s syndrome
  • neurological disorders in which there is a deficiency of nerve impulses that stimulate the pituitary gland and hypothalamus to produce thyroid hormones.

It should be added that iodine deficiency is an increasingly rare cause of the development of hypothyroidism, because iodine deficiencies in the diet are less frequent than in the past.

Hypothyroidism and Hashimoto’s disease

Hashimoto’s disease is the most common cause of hypothyroidism today. As the immune system malfunctions and attacks its own tissues, in this case the thyroid, thyroid problems are becoming more and more autoimmune. Hashimoto’s disease can develop latently or in its early stages, causing hyperthyroidism symptoms for a short period of time. However, it usually progresses to hypothyroidism, and treatment focuses on that.

Symptoms of hypothyroidism

Symptoms of hypothyroidism are most often the result of slowing down the activity of the body. Symptoms often associated with hypothyroidism include a tendency to gain weight , but the list of typical ailments is much longer.

The main symptoms of hypothyroidism are:

  • constant fatigue – inadequate to the effort,
  • drowsiness that does not go away despite drinking coffee or energy drinks,
  • problems with concentration and memory , and even memory loss or intellectual disorders that resemble dementia,
  • muscle weakness,
  • chronic  constipation ,
  • mood swings – especially despondency, indifference,  depression , apathy,
  • feeling cold – even when he is warmly dressed or in heated rooms,
  • decreased sweating, 
  • swelling of the face, eyelids, hands, resulting from the accumulation of mucous substance in the intercellular spaces (myxoedema),
  • pain, redness and burning of the eyes – the symptoms often resemble conjunctivitis,
  • decrease in immunity – the result is frequent infections,
  • problems with getting pregnant  or carrying it to term,
  • easy bruising,
  • tingling and numbness of the hands,
  • hair loss, paleness and dry skin.

If you notice that your neck circumference has increased for unknown reasons, go to your doctor and ask for a referral for thyroid tests..

The symptoms of hypothyroidism in the elderly are more difficult to spot because they are atypical. For this reason, hypothyroidism in the elderly is often misdiagnosed as atherosclerosis or depression.

Diagnosis

The diagnosis of hypothyroidism involves measuring the blood level of TSH and FT4, which are hormones produced by the pituitary gland. If the TSH level is too high, the body is trying to stimulate the thyroid gland to work more intensively.

TSH standards

TSH parameters vary from laboratory to laboratory, but normal values are usually between 0.4 and 4.0 mIU/l. However, a doctor must evaluate the result on an individual basis. Because an infection or chronic illness can artificially lower or increase a single result’s reliability, it is also crucial. If symptoms typical of hypothyroidism are present, it is worth repeating the examination or extending the current diagnostics.

Treatment of hypothyroidism

Treatment for hypothyroidism is the oral administration of synthetic hormones, such as levothyroxine. Levothyroxine is taken every morning on an empty stomach and should not be eaten for 30–60 minutes. The effectiveness of the therapy is high, and many symptoms disappear in a short time, but some patients still report some symptoms. To ensure the effectiveness of the therapy, TSH levels should be measured regularly, and in some 30–60 T4.